Lecture Exam 4 (Ch 12, 13, 14)

A  T-cell mediated

B  antibody mediated

C  atopic

D  delayed

E  systemic anaphylactic

A  maternal Rh ˗ cells enter an Rh + fetus

B  maternal Rh + cells enter an Rh -fetus

C  fetal Rh ˗ cells enter an Rh + mother

D  fetal Rh + cells enter an Rh + mother

E  fetal Rh + cells enter an Rh – mother

A  transfusion reaction

B  immunodeficiency

C  autoimmune disease

D  desensitization

E  hypersensitivity

A  immunopathology

B  humoralpathology

C  histopathology

D  epidemiology

E  hemopathology

A  foreign cells

B  complement

C  IgM

D  IgE

E  IgG

A  type I diabetes

B  Graves’ disease

C  metastatic cancer

D  rheumatic fever

E  systemic lupus erythematosus

A  allograft

B  hypograft

C  xenograft

D  autograft

E  isograft

F    

A  Ingestant

B  Injectant

C  Contactant

D  None of the choices are correct.

E  Inhalant

A  constriction of smooth muscle of bronchi and the intestine

B  wheal and flare reaction in skin

C  increased sensitivity to pain

D  relaxes vascular smooth muscle

E  pruritus and headache

A  type I and type IV

B  type I only

C  type I, type II, and type III

D  type IV only

E  type I, type II, type III, and type IV

A  a transfusion reaction

B  graft rejection

C  IgE and mast cells

D  autoantibodies and T cells

E  a deficiency in T-cell development

A  Rhinitis

B  Sneezing

C  Diarrhea

D  Rashes

E  Contact dermatitis

A  relieve inflammatory symptoms

B  inhibit the activity of lymphocytes

C  reverse spasms of respiratory smooth muscles

D  bind to histamine receptors on target organs

E  block synthesis of leukotrienes

A  Degranulation

B  Binding of IgE by the Fc region to mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Histamine acts on smooth muscle

A  sodium pump proteins in the cell membrane

B  myelin sheath cells of the nervous system

C  cells in thyroid follicles

D  acetylcholine receptors on smooth muscle

E  acetylcholine receptors on skeletal muscle

A  Involves production of IgG and IgE antibodies

B  The Arthus reaction is a local response

C  Involves an immune complex reaction

D  Serum sickness is a systemic response

E  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues

A  eczema

B  allergic rhinitis

C  anaphylaxis

D  atopic dermatitis

E  asthma

A  Blood transfusion

B  All of thechoices are correct.

C  Skin graft

D  Both skin graft and organ transplantation

E  Organ transplantation

A  sensitization

B  tissue matching

C  None of thechoices are correct.

D  degranulation

E  desensitization

A  Histamine acts on smooth muscle

B  Binding of IgE by the Fc region to mast cells and basophils

C  Prostaglandins cause vasodilation and increased vascular permeability

D  Bonding of allergen to adjacent IgE binding sites on mast cells and basophils

E  Degranulation

A  None of the choices are correct.

B  Hypogammaglobulinemia

C  Graft versus host disease

D  Formation of autoantibodies

E  Host rejection of graft

A  Anaphylaxis

B  Both antibody mediated and immune complex mediated

C  Immune complex mediated

D  Both anaphylaxis and antibody mediated

E  Antibody mediated

A  myasthenia gravis

B  rheumatoid arthritis

C  Graves’ disease

D  tuberculin reaction

E  multiple sclerosis

A  platelet-activating factor

B  leukotriene

C  serotonin

D  prostaglandin

E  histamine

A  two identical light polypeptide chains

B  two identical heavy polypeptide chains

C  four antigen binding sites

D  a variable and constant region on each polypeptide chain

E  disulfide bonds between polypeptide chains

A  All of the choices are correct.

B  hormonal signals that initiate development

C  release of mature lymphocytes to begin migration to various lymphoid organs

D  B cells maturing in bone marrow sites

E  T cells maturing in the thymus

A  terminal

B  Fab

C  variable

D  hinge

E  Fc

A  directly destroy target cells

B  suppress immune reactions

C  secrete antibodies

D  function in allergic reactions

E  activate B cells and other T cells

A  All of the choices are correct.

B  hold and present processed antigen on their cell membrane surface

C  include dendritic cells

D  engulf and modify antigen to be more immunogenic

E  include macrophages

A  true

B  false

A  typically a protein antigen

B  binding of T-cell to a class II MHC receptor on a macrophage

C    

D  All of the choices are correct.

E  interleukin-1 activating the T helper cell

F  binding of T-cell to a site on the antigen

A  IgE

B  IgA

C  IgM

D  IgD

E  IgG

A  activate B cells and other T cells

B  suppress immune reactions

C  function in allergic reactions

D  directly destroy target cells

E  secrete antibodies

A  epitope

B  hapten

C  antigen binding site

D  None of the choices are correct.

E  variable region

A  are the result of genetic expression

B  receive and transmit chemical messages among other cells of the system

C  function in recognition of self molecules

D  All of the choices are correct.

E  aid in cellular development

A  have large polymers made up of repeating subunits

B  are large molecules with a minimum molecular weight of 1,000

C  have molecular complexity

D  are foreign to the immune system

E  are cells or large, complex molecules

A  superantigens

B  None of the choices are correct.

C  heterophilic antigens

D  autoantigens

E  allergens

A  helper T cells

B  delayed hypersensitivity T cells

C  natural killer (NK) cells

D  cytotoxic T cells

E  suppressor T cells

A  B cells

B  Cytotoxic T cells

C  Helper T cells

D  Antigen-presenting cells

E  Plasma cells

A  All of the choices are correct.

B  self receptors recognized by T lymphocytes

C  all HLA antigens

D  certain secreted complement components

E  receptors located primarily on macrophages and B cells

A  false

B  true

A  contains a central J chain

B  is the first class synthesized by a plasma cell

C  has 10 antigen binding sites

D  can serve as a B-cell receptor

E  is a dimer

A  None of the choices are correct.

B  body tissues that the immune system mistakes as foreign

C  bacterial toxins that activate T cells at a 100 times greater rate than other antigens

D  those that evoke allergic reactions

E  cell markers found in some member of a species but not in other members

A  true

B  false

A  IgE

B  IgM

C  IgD

D  IgA

E  IgG

A  have membrane receptors that recognize foreign antigens

B  develop into clones of B and T cells with extreme variations of specificity

C  All of the choices are correct.

D  gain tolerance to self by destruction of lymphocytes that could react against self

E  possess MHC antigens for recognizing self

A    

B  located in the thymus gland

C  glycoproteins, called MHC antigens, found on all body cells

D  All of the choices are correct.

E  found on the third chromosome

F  a set of genes that code for MHC glycoproteins

A  leukocytes

B  red blood cells

C  epithelial cells

D  islet of Langerhans cells

E  eosinophils

A  IgG only

B  IgD only

C  IgD and IgE

D  IgM and IgD

E  IgM only

A  Urinary tract

B  Respiratory tract

C  Eyes

D  Digestive tract

E  Skin

A  increases phagocytosis

B  increases the availability of iron

C  increases metabolism

D  stimulates hematopoiesis

E  reduces the ability of temperature-sensitive organisms to multiply

A  Includes chemicals such as lysozyme and lactic acid
Involves barriers at portals of entry
Examples include the ciliated epithelium of the respiratory passages, excretion of urine, and production of tears

B  Involves barriers at portals of entry
Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

C  Involves phagocytic cells (neutrophils and macrophages)
Involves recognition of foreign agents by their pathogen-associated molecular patterns

D  Includes chemicals such as lysozyme and lactic acid
Involves recognition of foreign agents by their pathogen-associated molecular patterns

A  monocytes

B  neutrophils

C  eosinophils

D  basophils

E  lymphocytes

A  killer T cells

B  primary phagocytes

C  macrophages

D  cytotoxic T cells

E  neutrophils

A  eosinophils

B  mast cells

C  platelets

D  dendritic cells

E  macrophages

A  Basophils

B  Eosinophils

C  Monocytes

D  Neutrophils

E  Lymphocytes

A  pain

B  redness

C  swelling

D  warmth

E  chills

A  antigens

B  antibodies

C  lysozyme

D  histamine

E  digestive enzymes

A  None of the choices are correct.

B  granulocytes

C  leukocytes

D  monocytes

E  agranulocytes

A  Start tissue repair

B  Cause a fever

C  Block further invasion

D  Destroy microbes

E  Mobilize and attract immune components to injury site

A  production of only red blood cells

B  loss of blood due to hemorrhaging

C  production of white blood cells, red blood cells, and platelets

D  plugging of broken vessels to stop bleeding

E  migration of white blood cells from the blood out to the tissues

A  unbroken skin

B  T cells

C  tears

D  mucus

E  hairs

A  is the liquid portion of blood in which blood cells are suspended

B  All of the choices are correct.

C  is mostly water

D  contains fibrinogen

E  contains albumin and globulins

A  None of these are mismatched.

B  Dolar—pain

C  Calor—warmth

D  Tumor—cancer

E  Rubor—redness

A  Serotonin causes smooth muscle contraction.

B  Basophils and mast cells release histamine.

C  Fever could be beneficial to inhibiting the pathogen.

D  Pyrogens cause vasodilation and increased capillary permeability.

E  It can last hours to years.

A  eyes

B  respiratory tract

C  digestive tract

D  skin

E  urinary tract

A  Bloodstream

B  Intracellular fluid

C  Lymphatic system

D  Extracellular fluid

A  Monocytes; basophils

B  B cells; neutrophils

C  B cells; T cells

D  Basophils; T cells

E  T cells; B cells

A  Include erythrocytes that, when mature, lose their nuclei

B  Include leukocytes that are either granulocytes or agranulocytes

C  Develop from undifferentiated stem cells

D  After birth, produced in red bone marrow sites

E  Include Kupffer cells

A  vasodilation

B  motility

C  phagocytosis

D  diapedesis

E  chemotaxis

A  lymph nodes

B  GALT

C  spleen

D  tonsils

E  thymus

A  Internal cellular and chemical defenses
Phagocytosis and inflammation
Anatomical and physiological barriers

B  Internal cellular and chemical defenses
Use of drugs and antibiotics
Host defenses due to B and T cells and their products

C  Host defenses due to B and T cells and their products
Use of drugs and antibiotics
Anatomical and physiological barriers

D  Host defenses due to B and T cells and their products
Use of drugs and antibiotics

A  None of the choices are correct.

B  physically restricts pathogens to a specific region

C  destroys pathogens

D  creates a physical barrier against pathogens

E  is toxic to pathogens